Heart Health
Heart disease remains a leading cause of illness and death—and few areas of medicine are as crowded with dogma and confusion. In our Heart Health series, we cut through the noise and dive into the real nuances, complexities, and controversies with rigor and clarity.
Community Favorites
Heart Rate Variability (And the Coffee That Almost Killed Me)
This Statin Study Should Have Changed Medicine (Statin GLP-1)
Statins
When it comes to statins, patients deserve to understand what these drugs actually do in the body. In my experience—both as an MD-PhD and as a patient—there is a real shortage of rigorous, accessible information that allows patients and physicians to give truly informed consent. Time to fix that.
This Statin Study Should Have Changed Medicine (Statin GLP-1)
The Big New Statin Study (Lancet) Has a Big Blind Spot (Literally)
A Doctor Texted Me: “I’m Stopping My Statin” – Here’s Why (Statins and Muscles)
I Tried Statins – And Stopped. Here’s Why (Statins and Mitochondria)
The 12-Year-Old, The Statin, and The Stories We Tell Ourselves
Other (Non-Statin) Heart Health Pharmacotherapy
Will This Gene Editing Breakthrough Eliminate Heart Disease? (VERVE Study)
Obicetrapib (CEPT inhibitor): A New “Cholesterol” Drug for Alzheimer’s Disease
Heart Health Supplements
Beyond pharmaceuticals, there are natural compounds that may benefit heart health through surprisingly diverse mechanisms—touching many different aspects of metabolism. Here are a few.
Nattokinase: The Heart Health Supplement on Everyone’s Tongue
How TUDCA Shifts the Inflammatory Landscape of Heart Disease
Lp(a)
Lp(a) is cardiology’s latest obsession: a highly atherogenic lipoprotein that’s mostly genetically fixed—or so the story goes. The reality is more nuanced. Here’s what you need to know, and what you can actually do.
Heart Health, Other
There are countless corners of cardiology and heart health left to explore. Here are even more deep dives to help quench your curiosity.
Heart Rate Variability (And the Coffee That Almost Killed Me)
ApoB Alice: A Case Study in How to Think about High LDL & ApoB
Peter Attia is Hiding Something (But It’s Not What You Think)
Lowering Cholesterol Killed: A Study Buried for 40 Years (Minnesota Coronary Experiment)
The Saturated Fat Story Hit Another Plot Twist (Lyon Diet Heart)
What if the Statin Trial that Changed Medicine… Got it Half-Right (4S Trial)
Cholesterol and ApoB Don’t Predict Death. This Does (Metabolic Vulnerability)
This Simple Gut Molecule Could Protect Against a Heart Attack:


